How to take VELTASSA
How to store VELTASSA



How to take VELTASSA
How to store VELTASSA

What Is Veltassa?

Your doctor may have told you that you have high levels of potassium in your blood (also known as hyperkalemia). High potassium can cause health issues, including serious heart problems, for some people. The good news is that it can be treated.

VELTASSA is a sodium-free prescription medication used to treat high potassium. Taken once daily, a dose of VELTASSA can help reduce high potassium in the blood, and keep levels lower over time. It is not known if VELTASSA is safe or effective in children.

MOA Diagram

K is the scientific symbol for potassium

How does VELTASSA work?

VELTASSA binds with potassium in your gastrointestinal tract, primarily in the colon, or large intestine, where excess potassium is most common. Then, both the potassium and VELTASSA pass through and are removed from your body. VELTASSA is not absorbed by your body.

In a study, VELTASSA began reducing levels of potassium within hours, and potassium levels returned to a normal range within 2 days. Individual results may vary.

How do I get VELTASSA?

VELTASSA is available by prescription only. Talk to your doctor to see if VELTASSA is right for you.

In a study, up to 95% of patients taking VELTASSA each day for a year reached normal levels of potassium and stayed at normal levels
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Veltassa glass

HOW TO TAKE Veltassa

Color may vary.

Watch the “How to take VELTASSA” video below

  • VELTASSA is taken once a day with food
  • VELTASSA comes in single-use packets that you will mix with water
  • VELTASSA is an off-white to light brown powder. VELTASSA may occasionally vary in color when mixed with water. This variation in color does not affect the way VELTASSA works
  • In a small study, most people found that VELTASSA has no taste or smell

Take VELTASSA exactly as your doctor tells you to take it. Your doctor may change your dose if needed. Your doctor will check your potassium levels during treatment with VELTASSA.


  • Prepare each dose of VELTASSA separately
  • Follow the diet that your doctor has prescribed for you
  • Mix VELTASSA with water only

Do Not:

  • Do not take VELTASSA that has not been mixed with water
  • Do not heat, microwave, or add VELTASSA to heated food or liquids
  • Do not mix VELTASSA in a blender
3 Hours

Check the VELTASSA carton and packets once you receive your medication. Make sure the name “VELTASSA” is on the carton and packets. Call your doctor or pharmacist immediately and do not use medication if the seals on the carton are broken or missing OR if the expiration date on the carton or packets has passed.

How to prepare VELTASSA



Measure 1/3 cup of water in a measuring cup. Pour half of the water into an empty drinking glass. Pour all of the VELTASSA packet contents into the drinking glass with water.* Stir the mixture well.



Pour the rest of the water from the measuring cup into the drinking glass containing the mixture. Stir the mixture well. The powder will not dissolve and the mixture will look cloudy. If the mixture is too thick, you can add more water.



Drink the mixture right away. If any powder is left in the glass after drinking, add more water, stir the mixture, and drink the remaining mixture right away. Repeat as needed to make sure you take your entire dose of VELTASSA.

*You may need more than 1 packet of VELTASSA for your prescribed dose.
Make sure to follow the dosing instructions prescribed by your doctor.

1/3 cup

The recommended minimum amount of water for VELTASSA dose preparation is 1/3 cup (about 3 ounces).

The specified starting amount of water for all doses is about half of 1/3 cup. The remaining water should be added after stirring the powder in the starting amount of water.

How should I store Veltassa?


Store VELTASSA in the refrigerator at 36°F to 46°F (2°C to 8°C).


If VELTASSA cannot be stored in the refrigerator, it may be stored at room temperature, between 73°F to 81°F (23°C to 27°C), for up to 3 months. VELTASSA must be used within 3 months of being taken out of the refrigerator. Do not use VELTASSA after the expiration date printed on the packet.


Avoid exposing VELTASSA to heat above 104°F (40°C).

Important Safety Information

This information does not take the place of talking with your doctor about your medical condition or your treatment.

Who should not take Veltassa?

Do not take Veltassa if you are allergic to patiromer sorbitex calcium or any of the ingredients in Veltassa.

What should I tell my doctor before taking Veltassa?

Before you take Veltassa, tell your doctor about all of your medical conditions, including if you:

  • have problems having a bowel movement, including if you have severe constipation, a blockage (obstruction) in your bowel, or dry hard stool that will not pass out of your rectum (impaction)

  • have problems with your bowels after bowel surgery

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

What are the possible side effects of Veltassa?

Veltassa may cause serious side effects, including:

  • Low levels of magnesium in your blood (hypomagnesemia). Low levels of magnesium in the blood can happen when taking Veltassa. Your doctor will check the magnesium levels in your blood during treatment with Veltassa and may prescribe a magnesium supplement.

The most common side effects of Veltassa include: constipation, diarrhea, nausea, stomach-area (abdominal) discomfort, and gas.

Tell your doctor if you have any side effect that bothers you or does not go away.

These are not all of the possible side effects of Veltassa. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.1-800-FDA-1088.

General information about the safe and effective use of Veltassa

Do not take Veltassa for a condition for which it was not prescribed. Do not give Veltassa to other people, even if they have the same symptoms that you have. It may harm them. You can ask your doctor or pharmacist for information about Veltassa that is written for health professionals.

The risk information provided here is not comprehensive. To learn more, talk about Veltassa with your healthcare provider or pharmacist. Please see full Prescribing Information.

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